Karabina Sonia Athina

Karabina Sonia Athina

2010- : Professor of Cell Biology, UPMC Sorbonne Universités, Paris France
2003-2009: Senior Scientist, INSERM U937, Paris France.
2000-2003: Post Doctoral Fellow, Emory University, Atlanta, USA
1998-2000: Research associate, University of Ioannina, Greece
Part of the LEDUCQ Transatlantic Network of Excellence (2013-2018) « Understanding coronary artery disease genes” Coordinators: Pr. LUSIS, University of California, Los Angeles USA, Pr. SCHUNKERT, University of Lübeck (Germany)

Selected publications

1. Plasma PAFAH/PLA2G7 Genetic Variability, Cardiovascular Disease, and Clinical Trials. Karabina SA, Ninio E.
Enzymes. 2015;38:145-55. doi: 10.1016/bs.enz.2015.09.002. Epub 2015 Oct 17

2. Awad F, Georgin-Lavialle S, Brignier A, Derrieux C, Aouba A, Stankovic-Stojanovic K, Grateau G, Amselem S,
Hermine O, Karabina SA. Chronic myelomonocytic leukemia as a cause of fatal uncontrolled inflammation in
familial Mediterranean fever. Orphanet J Rare Dis. 2015 Jun 16;10:76. doi: 10.1186/s13023-015-0295-9.

3. Guardiola M, Exeter HJ, Perret C, Folkersen L, Van't Hooft F, Eriksson P, Franco-Cereceda A, Paulsson-Berne G,
Palmen J, Li K, Cooper JA, Khaw KT, Mallat Z, Ninio E, Karabina SA, Humphries SE, Boekholdt SM, Holmes
MV, Talmud PJ. PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk. Circ Cardiovasc
Genet. 2015 Apr;8(2):356-62. doi: 10.1161/CIRCGENETICS.114.000633. Epub 2015 Jan 12

4. Liu A, Ming JY, Fiskesund R, Ninio E, Karabina SA, Bergmark C, Frostegård AG, Frostegård J. Induction of
dendritic cell-mediated T-cell activation by modified but not native low-density lipoprotein in humans and inhibition
by annexin a5: involvement of heat shock proteins. Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):197-205

5. Penumetcha M, Schneider MK, Cheek HA, Karabina S. A diet containing soybean oil heated for three hours
increases adipose tissue weight but decreases body weight in C57BL/6 J mice. Lipids Health Dis. 2013 Mar 6;12:26.
doi: 10.1186/1476-511X-12-26.

6. Ait-Oufella H, Herbin O, Lahoute C, Coatrieux C, Loyer X, Joffre J, Laurans L, Ramkhelawon B, Blanc-Brude O,
Karabina S, Girard CA, Payré C, Yamamoto K, Binder CJ, Murakami M, Tedgui A, Lambeau G, Mallat Z. Group
X Secreted Phospholipase A2 Limits the Development of Atherosclerosis in LDL Receptor-Null Mice. Arterioscler
Thromb Vasc Biol. 2013 Mar;33(3):466-73. doi: 10.1161/ATVBAHA.112.300309. Epub 2013 Jan 24.

7. Atout R, Karabina SA, Dollet S, Carreras M, André P, Lambeau G, Lotteau V, Ninio E, Perrin-Cocon L. Human
group X secreted phospholipase A2 induces dendritic cell maturation through lipoprotein-dependent and -
independent mechanisms. Atherosclerosis 2012 222(2):367-74.

8. Gora S, Maouche S, Atout R, Wanherdrick K, Lambeau G, Cambien F, Ninio E, and Karabina S-A.
Phospholipolyzed LDL induces inflammatory response in endothelial cells through endoplasmic reticulum stress
signalling Faseb J 2010 24(9):3284-97.

9. De Keyzer D, Karabina S-A, Wei W, Geeraert B, Stengel D, Marsillach J, Camps J, Holvoet P, Ninio E. Increased
PAFAH and oxidized lipids are associated with inflammation and atherosclerosis in hypercholesterolemic pigs.
Arterioscl Thromb Vasc Biol 2009 (9):2041-2046

10. Gora S, Perret C, Jemel I, Nicaud V, Lambeau G, Cambien F, Ninio E, Blankenberg S, Tiret L, Karabina SA.
Molecular and functional characterization of polymorphisms in in the secreted phospholipase A2 group X gene.
Relevance to coronary artery disease. Journal of Molecular medicine 2009 87(7):723-33.

11. Karabina SA, Brocheriou I, Le Naour G, Agrapart M, Durand H, Gelb M, Lambeau G, Ninio E. Atherogenic
properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell
function. Faseb J 2006 (14):2547-2549

12. Gora S, Lambeau G, Bollinger JG, Gelb M, Ninio E, Karabina SA. The proinflammatory mediator Platelet
Activating Factor is an effective substrate for human group X secreted phospholipase A2. Biochim Biophys Acta
2006 1761(9):1093-9